Scotland has a major unmet need in translational imaging expertise to support its substantial strengths in medical research, including drug discovery. The initial SINAPSE Pooling investment in neuroimaging research increased expertise at all levels, in MRI, PET/SPECT, radiochemistry and functional imaging, and established an exemplary PhD programme and Imaging Trans-Skills Course.
Researchers today from many different disciplines rely on software to carry out high quality research. This software must be able to serve the changing needs of the researcher to remain relevant. It must be able to change, adapt, and travel with the researcher on the journey of exploration, innovation and discovery which embodies leading research.
The aim is to develop an open-access, automated, web-based platform for real-time data collation, analysis and information exchange for geophysical experiments. This scientific gateway should enable competing physical hypotheses and statistical methods for forecasting rock failure to be tested and developed in fully prospective mode in an open, testable environment comparable to say daily weather forecasts.
The investment in e-Science has delivered a huge impetus to UK research programmes but it has the potential to do much more. This potential will be realised in the UK only if we sustain the development of collaborative and cooperative research behaviour. Indeed we wish to extend it to far more participants, so that all researchers, designers and decision makers have the power of advanced e-Infrastructure at their finger tips. This requires continued collaboration to build that e-Infrastructure.
In order to maintain and integrate GridQTL with other resources we are requesting two full-time posts, one to be based at NeSC and the other at IEB. The principal tasks for these posts are outlined under the management structure. GridQTL, our existing project upon which GridQTL+ is based, is a collaborative project across three sites. The different expertise from each of these groups has been essential to the development of GridQTL and we wish to continue with this successful arrangement.
Studies have found that between 40 percent and 75 percent of older people do not take their medications at the right times or in the right amounts. The costs of poor adherence to medication (overdosing and under dosing) can be severe, both to the individual and in terms of potentially avoidable demand on health and social services. Adverse drug events and poor adherence are a common cause of hospitalisation in older people.
The main aim of this project is to remove the barrier of uptake to the seismology community of an application that allows analyses of seismic waveform data. This will be achieved by embedding this analysis application in a community gateway, which already exists in the form of a web portal.
3D developmental atlases are used in research for capture, collation and analysis of spatio-temporal data such as in situ gene-expression. The most advanced systems are based on a temporal series of 3D models. Examples are the EADHB human embryo atlas in Newcastle and the e-MouseAtlas in Edinburgh. Here we propose to use the 3D spatio-temporal frameworks in conjunction with a repository to deliver research and educational material directly in the context of the developing embryo.
The world of healthcare could be transformed by realistic models that capture the processes and disorders of the human brain – but creating these involves overcoming immense scientific and technological challenges. The aim of this Theme is to begin with a simpler, more tractable problem: simulating the brain of a fly.